Conditions
Cushing (PPID) in horses — symptoms & treatment
Cushing — or PPID — occurs mainly in older horses and ponies. Read about symptoms, diagnosis, treatment and how to properly care for a horse with Cushing's.
Published: 4/12/2026
EquiSight Editorial
Redactie · EquiSight · SaFleu Equestrian Centre BV
What is Cushing/PPID?
A hormonal disorder of the pituitary gland in which the horse produces too much ACTH. The result: uncontrolled coat growth, a weakened immune system and an increased risk of laminitis.
Symptoms
- Long, curly coat that fails to shed
- Excessive drinking and urination
- Muscle atrophy (especially the back and hindquarters)
- Fat deposits on the neck, withers and croup
- Increased susceptibility to infections
- Laminitis
Diagnosis
Blood test (ACTH measurement). Best performed in September–October when seasonal variation is at its most pronounced.
Treatment
Pergolide is the standard treatment. Lifelong, one tablet per day. Combine with good nutrition (low sugar, low starch), regular hoof checks and mindful grazing management.